Aqueous microwave chemistry: a clean and green synthetic tool for rapid drug discovery

被引：424

作者：

Polshettiwar, Vivek ^{[1
]}

Varma, Rajender S. ^{[1
]}

机构：

[1] US EPA, Natl Risk Management Res Lab, Sustainable Technol Div, Cincinnati, OH 45268 USA

来源：

CHEMICAL SOCIETY REVIEWS | 2008年 / 37卷 / 08期

关键词：

D O I：

10.1039/b716534j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of "Greener Organic Chemistry'' is due to the recognition that environmentally friendly products and processes will be economical in the long term as they circumvent the need for treating 'end-of-the-pipe' pollutants and by-products generated by conventional synthesis. The fundamentals and signi. cant outcomes of microwave-assisted organic synthesis in aqueous medium are summarized in this tutorial review, which have resulted in the development of relatively sustainable and environmentally benign protocols for the synthesis of drugs and. ne chemicals.

引用

页码：1546 / 1557

页数：12

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