A regioselective synthesis of 1-haloisoquinolines via ruthenium-catalyzed cyclization of O-methylbenzohydroximoyl halides with alkynes

被引：59

作者：

Chinnagolla, Ravi Kiran ^{[1
]}

Pimparkar, Sandeep ^{[1
]}

Jeganmohan, Masilamani ^{[1
]}

机构：

[1] Indian Inst Sci Educ & Res, Dept Chem, Pune 411021, Maharashtra, India

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 35期

关键词：

H BOND ACTIVATION; NITROGEN-CONTAINING HETEROCYCLES; ONE-POT SYNTHESIS; ISOQUINOLINIUM SALTS; PYRROLE SYNTHESIS; INTERNAL ALKYNES; C-C; PYRIDINES; COUPLING/CYCLIZATION; DERIVATIVES;

D O I：

10.1039/c3cc41269e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A ruthenium-catalyzed highly regioselective cyclization of substituted N-methoxy benzimidoyl halides with alkynes in the presence of CsOAc (25 mol%) to give substituted 1-halo and 1-alkoxy substituted isoquinolines in good to excellent yields is described.

引用

页码：3703 / 3705

页数：3

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