Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine

被引：976

作者：

Evans, Conor. L. ^{[1
]}

Xie, X. Sunney ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY | 2008年 / 1卷 / 01期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

Raman; CARS; molecular imaging; biomedical imaging; metabolic imaging; skin imaging;

D O I：

10.1146/annurev.anchem.1.031207.112754

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging technique that is capable of real-time, nonperturbative examination of living cells and organisms based on molecular vibrational spectroscopy. Recent advances in detection schemes, understanding of contrast mechanisms, and developments of laser sources have enabled superb sensitivity high time resolution. such as Metabolite and drug imaging and tumor identification, raise many exciting new possibilities for biology and medicine.

引用

页码：883 / 909

页数：27

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