G-quadruplex-based DNAzyme for facile colorimetric detection of thrombin

被引：139

作者：

Li, Tao

Wang, Erkang

Dong, Shaojun ^{[1
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 31期

关键词：

D O I：

10.1039/b805565c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thrombin-binding aptamer is found to bind hemin to form a catalytic complex whose activity is significantly promoted by the addition of thrombin, which enables the colorimetric detection of thrombin with high specificity and sensitivity in a facile way.

引用

页码：3654 / 3656

页数：3

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