Allosteric control of oligonucleotide hybridization by metal-induced cyclization

被引：42

作者：

Göritz, M ^{[1
]}

Krämer, R ^{[1
]}

机构：

[1] Heidelberg Univ, Inst Anorgan Chem, D-69120 Heidelberg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 51期

关键词：

D O I：

10.1021/ja056463s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A bis(terpyridine) modified single-stranded DNA smoothly forms a stable cycle by Fe2+-assisted ring closure. A novel, complex type of allosteric behavior is observed with Zn2+, which reversibly off-regulates binding of a complementary oligonucleotide only in a narrow concentration range. Copyright © 2005 American Chemical Society.

引用

页码：18016 / 18017

页数：2

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