How LFA-1 binds to different ligands

被引：46

作者：

Binnerts, ME ^{[1
]}

van Kooyk, Y ^{[1
]}

机构：

[1] Univ Nijmegen, Dept Tumor Immunol, Nijmegen, Netherlands

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 05期

关键词：

D O I：

10.1016/S0167-5699(99)01467-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The integrin leukocyte function-associate antigen 1 (LFA-1) is pivotal for cell adhesion and signalling within the immune system. Here, Minke Binnerts and Yvette van Kooyk discuss evidence from mutational and crystallographic studies showing that binding of LFA-1 to its ligands intercellular adhesion molecule 1 (ICAM-1), -2 and -3 might be structurally distinct.

引用

页码：240 / 245

页数：6

共 44 条

[11] Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1
Edwards, CP
Fisher, KL
Presta, LG
Bodary, SC
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (44) : 28937 - 28944
[12] Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1
Fisher, KL
Lu, J
Riddle, L
Kim, KJ
Presta, LG
Bodary, SC
[J]. MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (03) : 501 - 515
[13] Identifying the putative metal ion-dependent adhesion site in the beta(2) (CD18) subunit required for alpha(L)beta(2) and alpha(M)beta(2) ligand interactions
Goodman, TG
Bajt, ML
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (39) : 23729 - 23736
[14] ANALYSIS OF THE BINDING-SITE ON INTERCELLULAR-ADHESION MOLECULE-3 FOR THE LEUKOCYTE INTEGRIN LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1
HOLNESS, CL
BATES, PA
LITTLER, AJ
BUCKLEY, CD
MCDOWALL, A
BOSSY, D
HOGG, N
SIMMONS, DL
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (02) : 877 - 884
[15] A BINDING INTERFACE ON THE I-DOMAIN OF LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 (LFA-1) REQUIRED FOR SPECIFIC INTERACTION WITH INTERCELLULAR-ADHESION MOLECULE-1 (ICAM-1)
HUANG, CC
SPRINGER, TA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (32) : 19008 - 19016
[16] Integrin activation: The link between ligand binding and signal transduction
Humphries, MJ
[J]. CURRENT OPINION IN CELL BIOLOGY, 1996, 8 (05) : 632 - 640
[17] CRITICAL THREONINE AND ASPARTIC-ACID RESIDUES WITHIN THE I-DOMAINS OF BETA-2 INTEGRINS FOR INTERACTIONS WITH INTERCELLULAR-ADHESION MOLECULE-1 (ICAM-1) AND C3BI
KAMATA, T
WRIGHT, R
TAKADA, Y
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (21) : 12531 - 12535
[18] Localization of the binding site on intercellular adhesion molecule-3 (ICAM-3) for lymphocyte function-associated antigen 1 (LFA-1)
Klickstein, LB
York, MR
deFougerolles, AR
Springer, TA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (39) : 23920 - 23927
[19] PRIMARY STRUCTURE OF THE LEUKOCYTE FUNCTION ASSOCIATED MOLECULE-1 ALPHA-SUBUNIT - AN INTEGRIN WITH AN EMBEDDED DOMAIN DEFINING A PROTEIN SUPERFAMILY
LARSON, RS
CORBI, AL
BERMAN, L
SPRINGER, T
[J]. JOURNAL OF CELL BIOLOGY, 1989, 108 (02) : 703 - 712
[20] CRYSTAL-STRUCTURE OF THE A-DOMAIN FROM THE A-SUBUNIT OF INTEGRIN CR3 (CD11B/CD18)
LEE, JO
RIEU, P
ARNAOUT, MA
LIDDINGTON, R
[J]. CELL, 1995, 80 (04) : 631 - 638

← 1 2 3 4 5 →