Toward a New Toxicology - Evolution or Revolution?

被引:34
作者
Hartung, Thomas [1 ,2 ]
机构
[1] European Commiss Joint Res Ctr, Inst Protect & Secur Citizen, Traceabil Risk & Vulnerabil Assessment Unit, I-21027 Ispra, VA, Italy
[2] Univ Konstanz, Constance, Germany
来源
ATLA-ALTERNATIVES TO LABORATORY ANIMALS | 2008年 / 36卷 / 06期
关键词
alternatives; animal testing; new approaches and technologies; philosophy; risk assessment; safety assessment; toxicology;
D O I
10.1177/026119290803600607
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
This essay summarises the author's thoughts on the current paradigm change in toxicology. The driving factors and mechanisms of this change, and obstacles to it, are discussed. Current developments are discussed on the basis of some key assumptions in Thomas Kuhn's famous book, The Structure of Scientific Revolutions. The author's personal view is that there is clear evidence that revolutionary changes in regulatory toxicology are emerging.
引用
收藏
页码:635 / 639
页数:5
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