Fungal urinary tract infections in patients at risk

被引:20
作者
Krcmery, S
Dubrava, M
Krcmery, V
机构
[1] Comenius Univ, Dept Geriatr Med, Sch Med, Bratislava 83101, Slovakia
[2] St Elisabeth Canc Inst, Dept Clin Pharmacol, Bratislava, Slovakia
关键词
fungal urinary tract infection; systemic antifungals; high-risk patients;
D O I
10.1016/S0924-8579(99)00032-1
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Fungal urinary tract infection (UTI) represents a high-risk event in severely ill patients. Its increasing incidence in recent years is associated with extensive and prolonged use of broad-spectrum antimicrobial agents, corticosteroids, immunosuppressive and cytotoxic drugs. Other important risk factors comprise higher age, diabetes mellitus, chronic renal failure, hemodialysis, renal transplantation, structural or functional abnormalities of urinary tract with indwelling urinary catheter or nephrostomy. Fifty hospitalized symptomatic patients with funguria of > 10(5) CFU/ml and leucocyturia were analysed for etiology, risk factors and outcome. Candida albicans was isolated in 36 patients, non-albicans Candida species (Candida tropicalis, Candida krusei) and non-Candida yeasts (Blastoschizomyces capitatus) in 14 patients, respectively. All patients were treated with systemic antifungals. In total, 42 patients of 50 (84%) were cured (32/36 with C. albicans and 10/14 with non-C. albicans associated funguria). Systemic antifungal therapy should be considered in high-risk patients with fungal UTI. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:289 / 291
页数:3
相关论文
共 17 条
  • [11] KREMERY S, 1997, URINARY TRACT INFECT, P48
  • [12] Funguria in cancer patients: Analysis of risk factors, clinical presentation and outcome in 50 patients
    Oravcova, E
    Lacka, J
    Drgona, L
    Studena, M
    Sevcikova, L
    Spanik, S
    Svec, J
    Kukuckova, E
    Grey, E
    Silva, J
    Krcmery, V
    [J]. INFECTION, 1996, 24 (04) : 319 - 323
  • [13] INFECTIOUS-DISEASE COMPLICATIONS OF RENAL-TRANSPLANTATION
    RUBIN, RH
    SNYDMAN, D
    HARRINGTON, JT
    MADIAS, NE
    KING, A
    MYER, K
    SINGH, A
    [J]. KIDNEY INTERNATIONAL, 1993, 44 (01) : 221 - 236
  • [14] THE ENIGMA OF CANDIDURIA - EVOLUTION OF BLADDER IRRIGATION WITH AMPHOTERICIN-B FOR MANAGEMENT - FROM ANECDOTE TO DOGMA AND A LESSON FROM MACHIAVELLI
    SANFORD, JP
    [J]. CLINICAL INFECTIOUS DISEASES, 1993, 16 (01) : 145 - 147
  • [15] vantWout JW, 1996, EUR J CLIN MICROBIOL, V15, P238, DOI 10.1007/BF01591361
  • [16] GENITOURINARY CANDIDIASIS - DIAGNOSIS AND TREATMENT
    WISE, GJ
    GOLDBERG, P
    KOZINN, PJ
    [J]. JOURNAL OF UROLOGY, 1976, 116 (06) : 778 - 780
  • [17] AMPHOTERICIN-B AS A UROLOGIC IRRIGANT IN THE MANAGEMENT OF NON-INVASIVE CANDIDURIA
    WISE, GJ
    KOZINN, PJ
    GOLDBERG, P
    [J]. JOURNAL OF UROLOGY, 1982, 128 (01) : 82 - 84