Isolation, structure and bioactivities of the polysaccharides from Angelica sinensis (Oliv.) Diels: A review

被引：435

作者：

Jin, Mingliang ^{[1
]}

Zhao, Ke ^{[2
]}

Huang, Qingsheng ^{[1
]}

Xu, Chunlan ^{[1
]}

Shang, Peng ^{[1
]}

机构：

[1] Northwestern Polytech Univ, Inst Special Environm Biophys, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Xian 710072, Peoples R China

[2] Xi An Jiao Tong Univ, Coll Med, Xian 710061, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2012年 / 89卷 / 03期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

Polysaccharide; Angelica sinensis; Structure; Biological activities; MACROPHAGE ACTIVATION; APOPTOSIS; ANTITUMOR; INJURY; CELLS; PROLIFERATION; MODULATION; EXTRACTION; HEPCIDIN; FEATURES;

D O I：

10.1016/j.carbpol.2012.04.049

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

The root of Angelica sinensis (Oliv.) Diels, a well-known Chinese herbal medicine, has been used historically as a tonic, hematopoietic and anti-inflammatory agent for thousands of years. Modern phytochemistry and pharmacological experiments have proved that polysaccharide is one of the major active ingredients in A. sinensis. It has been demonstrated that A. sinensis polysaccharides had various important biological activities, such as hematopoiesis, immunomodulation, antitumor, antioxidant, radioprotection and hypoglycemic activity. The purpose of the present review is to summarize previous and current references regarding extraction and purification techniques as well as structural characterization and biological activities of A. sinensis polysaccharides. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：713 / 722

页数：10

共 83 条

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[2]

A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway [J].