Genetic effects of radio-frequency, atmospheric-pressure glow discharges with helium

被引：151

作者：

Li, Guo ^{[1
]}

Li, He-Ping ^{[1
]}

Wang, Li-Yan ^{[2
]}

Wang, Sen ^{[1
]}

Zhao, Hong-Xin ^{[2
]}

Sun, Wen-Ting ^{[1
]}

Xing, Xin-Hui ^{[2
]}

Bao, Cheng-Yu ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Engn Phys, Beijing 100084, Peoples R China

[2] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China

来源：

APPLIED PHYSICS LETTERS | 2008年 / 92卷 / 22期

关键词：

D O I：

10.1063/1.2938692

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Due to low gas temperatures and high densities of active species, atmospheric-pressure glow discharges (APGDs) would have potential applications in the fields of plasma-based sterilization, gene mutation, etc. In this letter, the genetic effects of helium radio-frequency APGD plasmas with the plasmid DNA and oligonucleotide as the treated biomaterials are presented. The experimental results show that it is the chemically active species, instead of heat, ultraviolet radiation, intense electric field, and/or charged particles, that break the double chains of the plasmid DNA. The genetic effects depend on the plasma operating parameters, e.g., power input, helium flow rate, processing distance, time, etc. (C) 2008 American Institute of Physics.

引用

页数：3

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