Hydrodynamically Driven Self-Assembly of Giant Vesicles of Metal Nanoparticles for Remote-Controlled Release

被引:125
作者
He, Jie [1 ]
Wei, Zengjiang [1 ,2 ]
Wang, Lei [1 ,3 ]
Tomova, Zuleykhan [1 ]
Babu, Taarika [1 ]
Wang, Chaoyang [2 ]
Han, Xiaojun [3 ]
Fourkas, John T. [1 ,4 ]
Nie, Zhihong [1 ]
机构
[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA
[2] S China Univ Technol, Res Inst Mat Sci, Guangzhou 510640, Guangdong, Peoples R China
[3] Harbin Inst Technol, Sch Chem Engn & Technol, Harbin 150001, Peoples R China
[4] Univ Maryland, Inst Phys Sci & Technol, College Pk, MD 20742 USA
关键词
giant vesicles; nanoparticles; photothermal effect; plasmonic properties; self-assembly; POLYMER VESICLES; DRUG-DELIVERY; GOLD NANORODS; LIPOSOMES; ENCAPSULATION; FABRICATION; MICELLE;
D O I
10.1002/anie.201208425
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The hydrodynamics of laminar flow in a microfluidic device has been used to control the continuous self-assembly of gold nanoparticles (NPs) tethered with amphiphilic block copolymers. Spherical micelles, giant vesicles (500 nm-2.0 μm), or disk-like micelles could be formed by varying the flow rates of fluids. Such vesicles can release encapsulated hydrophilic species by using near-IR light (see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2463 / 2468
页数:6
相关论文
共 62 条
[1]   Development of inherently echogenic liposomes as an ultrasonic contrast agent [J].
AlkanOnyuksel, H ;
Demos, SM ;
Lanza, GM ;
Vonesh, MJ ;
Klegerman, ME ;
Kane, BJ ;
Kuszak, J ;
McPherson, DD .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1996, 85 (05) :486-490
[2]   Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions [J].
Alkilany, Alaaldin M. ;
Thompson, Lucas B. ;
Boulos, Stefano P. ;
Sisco, Patrick N. ;
Murphy, Catherine J. .
ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 (02) :190-199
[3]   Self-assembled nanorod supercrystals for ultrasensitive SERS diagnostics [J].
Alvarez-Puebla, Ramon A. ;
Zubarev, Eugene R. ;
Kotov, Nicholas A. ;
Liz-Marzan, Luis M. .
NANO TODAY, 2012, 7 (01) :6-9
[4]   Traps and cages for universal SERS detection [J].
Alvarez-Puebla, Ramon A. ;
Liz-Marzan, Luis M. .
CHEMICAL SOCIETY REVIEWS, 2012, 41 (01) :43-51
[5]  
[Anonymous], 2010, ANGEW CHEM, DOI DOI 10.1002/ange.201001373
[6]   Vesicles and liposomes:: A self-assembly principle beyond lipids [J].
Antonietti, M ;
Förster, S .
ADVANCED MATERIALS, 2003, 15 (16) :1323-1333
[7]   Directional Double Fano Resonances in Plasmonic Hetero-Oligomers [J].
Artar, Alp ;
Yanik, Ahmet Ali ;
Altug, Hatice .
NANO LETTERS, 2011, 11 (09) :3694-3700
[8]  
Christian DA, 2009, NAT MATER, V8, P843, DOI [10.1038/NMAT2512, 10.1038/nmat2512]
[9]   Polymer vesicles [J].
Discher, DE ;
Eisenberg, A .
SCIENCE, 2002, 297 (5583) :967-973
[10]   Giant vesicles as cell models [J].
Fenz, Susanne F. ;
Sengupta, Kheya .
INTEGRATIVE BIOLOGY, 2012, 4 (09) :982-995