Self-assembled nanorod supercrystals for ultrasensitive SERS diagnostics

被引：54

作者：

Alvarez-Puebla, Ramon A. ^{[1
]}

Zubarev, Eugene R. ^{[2
]}

Kotov, Nicholas A. ^{[3
,4
,5
]}

Liz-Marzan, Luis M. ^{[1
]}

机构：

[1] Univ Vigo, Dept Quim Fis, Vigo 36310, Spain

[2] Rice Univ, Dept Chem, Houston, TX 77005 USA

[3] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Dept Mat Sci, Ann Arbor, MI 48109 USA

[5] Univ Michigan, Dept Engn, Ann Arbor, MI 48109 USA

来源：

NANO TODAY | 2012年 / 7卷 / 01期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

SERS; Nanorods; Supercrystals; Diagnosis; Prions; ENHANCED RAMAN-SPECTROSCOPY; NANOSHELLS; PRIONS;

D O I：

10.1016/j.nantod.2011.11.001

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The fabrication of highly optically active supercrystals of anisotropic nanorods exploiting the electric field concentration and the nanoantenna effects provides a new family of optical sensors with the potential to maximize the SERS signal and thereby the possibility of detecting and quantifying the disease markers with low SERS cross-sections at ultralow concentrations. The capabilities of the new self-assembled nanorod SERS substrates have been demonstrated for real-time sensing of prions in real blood. It may also be possible to functionalize the top layers of supercrystals with specific recognition molecules for sensing many other disease markers, or even its integration into on-line devices, for the ultrasensitive screening of analytical targets relevant to medical science, environment, and homeland security. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：6 / 9

页数：4

共 13 条

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