Total synthesis and bioactivity of some naturally occurring pterulones

被引：21

作者：

Gruijters, BWT ^{[1
]}

van Veldhuizen, A ^{[1
]}

Weijers, CAGM ^{[1
]}

Wijnberg, JBPA ^{[1
]}

机构：

[1] Univ Wageningen & Res Ctr, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 04期

关键词：

D O I：

10.1021/np010510m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The naturally occurring pterulones 1, 3, and 13 were synthesized in high overall yield from readily available methyl 3-(2-propenyl)-4-(2-propenyloxy)benzoate (6) by employing ring-closing metathesis (RCM) as a key step. The biological activities of the synthesized pterulones were tested using cells of Rhodotorula glutinis and Saccharomyces cerevisiae.

引用

页码：558 / 561

页数：4

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