Genetic control of cortical regionalization and connectivity

被引：186

作者：

Rubenstein, JLR

Anderson, S

Shi, LM

Miyashita-Lin, E

Bulfone, A

Hevner, R

机构：

[1] Univ Calif San Francisco, Dept Psychiat, Ctr Neurobiol & Psychiat, Nina Ireland Lab Dev Neurobiol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Program Neurosci, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Program Dev Biol, San Francisco, CA 94143 USA

[4] Univ Calif San Francisco, Program Biomed Sci, San Francisco, CA 94143 USA

[5] Tigem Telethon Inst Genet & Med, I-20132 Milan, Italy

来源：

CEREBRAL CORTEX | 1999年 / 9卷 / 06期

关键词：

D O I：

10.1093/cercor/9.6.524

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Herein, the genetic control of regionalization and connectivity of the neocortex are reviewed. Evidence is accumulating which suggests that intrinsic mechanisms have a central role in controlling cortical regional specification and differentiation. Expression patterns of several genes (ld-2, Tbr-1, cadherin-6, cadherin-8, neuropilin-2, Wnt-7b, Eph-A7 and RZR-beta) are described; the expressions of these genes have regional boundaries which demarcate distint functional areas of the cerebral cortex in neonatal mice.

引用

页码：524 / 532

页数：9

共 88 条

[41]

2-P

[42]

KADESCH T, 1993, CELL GROWTH DIFFER, V4, P49

[43]

KAWANO H, 1999, IN PRESS J COMP NEUR

[44] THE FORMATION OF A CORTICAL SOMATOTOPIC MAP [J].

KILLACKEY, HP ;

RHOADES, RW ;

BENNETTCLARKE, CA .

TRENDS IN NEUROSCIENCES, 1995, 18 (09) :402-407

[45] THE ORGANIZATION OF NEOCORTEX IN MAMMALS - ARE SPECIES-DIFFERENCES REALLY SO DIFFERENT [J].

KRUBITZER, L .

TRENDS IN NEUROSCIENCES, 1995, 18 (09) :408-417

[46] Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord [J].

Lee, KJ ;

Mendelsohn, M ;

Jessell, TM .

GENES & DEVELOPMENT, 1998, 12 (21) :3394-3407

[47] Patterning and specification of the cerebral cortex [J].

Levitt, P ;

Barbe, MF ;

Eagleson, KL .

ANNUAL REVIEW OF NEUROSCIENCE, 1997, 20 :1-24

[48]

Livy DJ, 1997, HIPPOCAMPUS, V7, P2, DOI 10.1002/(SICI)1098-1063(1997)7:1<2::AID-HIPO2>3.3.CO

[49]

2-K

[50]

MARTINEZ S, 1999, IN PRESS DEVELOPMENT

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