Tissue Engineering at the Micro-Scale

被引：134

作者：

Bhatia, Sangeeta N. ^{[1
]}

Chen, Christopher S. ^{[2
]}

机构：

[1] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA

[2] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD USA

来源：

BIOMEDICAL MICRODEVICES | 1999年 / 2卷 / 02期

关键词：

CAD; computer-aided design; ECM; extracellular matrix; PMMA; polymethyl methacrylate; PDMS; polydimethyl siloxane; PLA; polylactic acid; PLGA; polylactic; (co-glycolic); acid; SFF; solid freeform fabrication; TEMP; tissue engineered medical product;

D O I：

10.1023/A:1009949704750

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The possibility to replace damaged or diseased organs with artificial tissues engineered from a combination of living cells and biocompatible scaffolds is becoming a reality through multidisciplinary efforts. A number of critical components within this effort are being facilitated by microfabrication and MEMS approaches, including research tools to elucidate mechanisms which control cellular behavior as well as development of methods to manufacture cellular scaffolds at ever higher resolutions. This article reviews recent advances in tissue engineering that have been facilitated by interaction with the microfabrication community. We highlight the potential opportunities for microfabrication to make to the development of mainstream medical therapies for tissue replacement.

引用

页码：131 / 144

页数：14

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