Synthesis of novel proline and γ-lactam derivatives as non-peptide mimics of Somatostatin/Sandostatin®

被引：22

作者：

Damour, D ^{[1
]}

Herman, F ^{[1
]}

Labaudinière, R ^{[1
]}

Pantel, G ^{[1
]}

Vuilhorgne, M ^{[1
]}

Mignani, S ^{[1
]}

机构：

[1] Rhone Poulenc Rorer SA, Ctr Rech Vitry Alfortville, F-94403 Vitry, France

来源：

TETRAHEDRON | 1999年 / 55卷 / 33期

关键词：

D O I：

10.1016/S0040-4020(99)00561-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Original proline or gamma-lactam derivatives bearing either an aryl group such as a phenyl or a 3-indolyl in position 3 of the proline moiety or on the 3-methyl chain of the gamma-lactam skeleton were prepared as nonpeptide mimics of Somatostatin/Sandostatin(R). (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：10135 / 10154

页数：20

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