Synthesis of the C6-C16 polyene fragment of ratjadone, a potent cytotoxic metabolite from Sorangium cellulosum

被引：14

作者：

Claus, E ^{[1
]}

Kalesse, M ^{[1
]}

机构：

[1] Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(99)00716-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd-catalyzed synthesis of the polyene fragment of ratjadone is described. This strategy employs the Stille-coupling for the coupling of the tetrahydropyran subunit and the Suzuki coupling for attaching the unsaturated lactone to the polyene chain. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4157 / 4160

页数：4

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