Interferometric fiber-based optical biosensor to measure ultra-small changes in refractive index

被引：11

作者：

Akkin, T ^{[1
]}

Davé, DP ^{[1
]}

Milner, TE ^{[1
]}

Rylander, HG ^{[1
]}

机构：

[1] Univ Texas, Austin, TX 78712 USA

来源：

OPTICAL FIBERS AND SENSORS FOR MEDICAL APPLICATIONS II | 2002年 / 4616卷

关键词：

refractive index; birefringence; biosensor; phase sensitive; fiber; interferometer;

D O I：

10.1117/12.463805

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In many bio-medical optical imaging applications such as monitoring cell and tissue dynamics and imaging of phase objects, ultra-small changes in refractive index must be detected. We describe a fiber-based optical biosensor, which is capable of detecting ultra-small refractive index changes in highly scattering media with high lateral and longitudinal spatial resolution. The system is a dual channel phase-sensitive optical low coherence tomography system that measures relative optical path length differences between the orthogonal modes of the polarization-maintaining fiber.

引用

页码：9 / 13

页数：5

共 4 条

[1] Optical low-coherence reflectometer for differential phase measurement [J].