Polarization oxygen sensor: a template for a class of fluorescence based sensors

被引:12
作者
Kostov, Y
Gryczynski, Z
Rao, G
机构
[1] Univ Maryland Baltimore Cty, Dept Chem & Biochem Engn, Baltimore, MD 21250 USA
[2] Univ Maryland, Sch Med, Ctr Fluorescence Spect, Baltimore, MD 21201 USA
关键词
D O I
10.1021/ac0111107
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We describe a novel oxygen polarization sensor based on a single molecule that changes the observed anisotropy of its emission with variation of the oxygen concentration. The approach is demonstrated both in solution and in solid films. A simple mathematical description of the sensor is included and experimentally verified. The technique demonstrated here creates opportunity for development of a new class of polarization-based dyes and sensors.
引用
收藏
页码:2167 / 2171
页数:5
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