Syntheses of five potential heterocyclic amine food mutagens

被引：9

作者：

Tanga, MJ

Bupp, JE

Tochimoto, TK

机构：

[1] SRI International, Menlo Park, CA 94025

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 03期

关键词：

D O I：

10.1002/jhet.5570340303

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of the potential heterocyclic amine food mutagens, 3,5,7-trimethyl-2-aminoimidazo[4,5-b]pyridine, 1,4,7-trimethyl-2-aminoimidazo[4,5-c]pyridine, 1,6,7-trimethyl-2-aminoimidazo[4,5-c]pyridine, 3,4,6-trimethyl-2-aminoimidazo[4,5-c]pyridine, and 1,4,6-trimethyl-7-aminoimidazo[4,5-c]pyridine are described.

引用

收藏

页码：717 / 727

页数：11

相关论文

共 14 条

[1] ISOLATION AND IDENTIFICATION OF MUTAGENS FROM A FRIED NORWEGIAN MEAT PRODUCT [J].

BECHER, G ;

KNIZE, MG ;

NES, IF ;

FELTON, JS .

CARCINOGENESIS, 1988, 9 (02) :247-253

[2] COMPARATIVE CARCINOGENICITY OF 4-AMINOBIPHENYL AND THE FOOD PYROLYSATES, GLU-P-1, IQ, PHIP, AND MEIQX IN THE NEONATAL B6C3F1 MALE-MOUSE [J].

DOOLEY, KL ;

VONTUNGELN, LS ;

BUCCI, T ;

FU, PP ;

KADLUBAR, FF .

CANCER LETTERS, 1992, 62 (03) :205-209

[3] FOOD-BORNE HETEROCYCLIC AMINES - CHEMISTRY, FORMATION, OCCURRENCE AND BIOLOGICAL-ACTIVITIES - A LITERATURE-REVIEW [J].

EISENBRAND, G ;

TANG, W .

TOXICOLOGY, 1993, 84 (1-3) :1-82

[4]

FELTON JS, 1992, CANCER RES, V52, pS2103

[5] IDENTIFICATION OF THE MUTAGENS IN COOKED BEEF [J].

FELTON, JS ;

KNIZE, MG ;

SHEN, NH ;

ANDRESEN, BD ;

BJELDANES, LF ;

HATCH, FT .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1986, 67 :17-24

[6]

JAGERSTAD M, 1983, ACS SYM SER, V215, P507

[7]

JAGERSTAD M, 1986, GENETIC TOXICOLOGY D, P155

[8]

Krimen L. I., 1988, ORG SYNTH, V6, P8

[9] CANCER RISK OF HETEROCYCLIC AMINES IN COOKED FOODS - AN ANALYSIS AND IMPLICATIONS FOR RESEARCH [J].

LAYTON, DW ;

BOGEN, KT ;

KNIZE, MG ;

HATCH, FT ;

JOHNSON, VM ;

FELTON, JS .

CARCINOGENESIS, 1995, 16 (01) :39-52

[10] INFLUENCE OF CREATINE, AMINO-ACIDS AND WATER ON THE FORMATION OF THE MUTAGENIC HETEROCYCLIC AMINES FOUND IN COOKED MEAT [J].

OVERVIK, E ;

KLEMAN, M ;

BERG, I ;

GUSTAFSSON, JA .

CARCINOGENESIS, 1989, 10 (12) :2293-2301