Chromatin and epigenetic determinants of estrogen receptor alpha (ESR1) signaling

被引：38

作者：

Magnani, Luca ^{[1
]}

Lupien, Mathieu ^{[1
]}

机构：

[1] Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON, Canada

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2014年 / 382卷 / 01期

关键词：

Epigenetic; Chromatin; Estrogen receptor; Transcriptional regulation; Pioneer factor; FOXA1; DNASE-I HYPERSENSITIVITY; LONG-RANGE INTERACTION; ER-ALPHA; RESPONSIVE PROMOTERS; REGULATORY ELEMENTS; ANDROGEN RECEPTOR; DISTAL ENHANCER; PIONEER FACTORS; NONCODING RNAS; CHIP-SEQ;

D O I：

10.1016/j.mce.2013.04.026

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The oestrogen receptor alpha (ESR1) is a transcription factor that potentiates the response to diverse stimuli, including oestrogen and growth factors, in various tissue types. Its recruitment to the DNA is directly regulated by the chromatin landscape, inclusive of chromatin compaction and epigenetic modifications. In this review we discuss our current understanding of the interplay between ESR1 signaling and the chromatin landscape. We present how the chromatin landscape primes the lineage-specific response and contributes to stimuli-specific signaling. Finally, we discuss recent efforts to decipher the relationship between genetic and epigenetic as it relates to ESR1 signaling in breast cancer. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：633 / 641

页数：9

共 117 条

[21] Whole-genome analysis informs breast cancer response to aromatase inhibition [J].

Ellis, Matthew J. ;

Ding, Li ;

Shen, Dong ;

Luo, Jingqin ;

Suman, Vera J. ;

Wallis, John W. ;

Van Tine, Brian A. ;

Hoog, Jeremy ;

Goiffon, Reece J. ;

Goldstein, Theodore C. ;

Ng, Sam ;

Lin, Li ;

Crowder, Robert ;

Snider, Jacqueline ;

Ballman, Karla ;

Weber, Jason ;

Chen, Ken ;

Koboldt, Daniel C. ;

Kandoth, Cyriac ;

Schierding, William S. ;

McMichael, Joshua F. ;

Miller, Christopher A. ;

Lu, Charles ;

Harris, Christopher C. ;

McLellan, Michael D. ;

Wendl, Michael C. ;

DeSchryver, Katherine ;

Allred, D. Craig ;

Esserman, Laura ;

Unzeitig, Gary ;

Margenthaler, Julie ;

Babiera, G. V. ;

Marcom, P. Kelly ;

Guenther, J. M. ;

Leitch, Marilyn ;

Hunt, Kelly ;

Olson, John ;

Tao, Yu ;

Maher, Christopher A. ;

Fulton, Lucinda L. ;

Fulton, Robert S. ;

Harrison, Michelle ;

Oberkfell, Ben ;

Du, Feiyu ;

Demeter, Ryan ;

Vickery, Tammi L. ;

Elhammali, Adnan ;

Piwnica-Worms, Helen ;

McDonald, Sandra ;

Watson, Mark .

NATURE, 2012, 486 (7403) :353-360

[22] Mapping and analysis of chromatin state dynamics in nine human cell types [J].

Ernst, Jason ;

Kheradpour, Pouya ;

Mikkelsen, Tarjei S. ;

Shoresh, Noam ;

Ward, Lucas D. ;

Epstein, Charles B. ;

Zhang, Xiaolan ;

Wang, Li ;

Issner, Robbyn ;

Coyne, Michael ;

Ku, Manching ;

Durham, Timothy ;

Kellis, Manolis ;

Bernstein, Bradley E. .

NATURE, 2011, 473 (7345) :43-U52

[23] Discovery and characterization of chromatin states for systematic annotation of the human genome [J].

Ernst, Jason ;

Kellis, Manolis .

NATURE BIOTECHNOLOGY, 2010, 28 (08) :817-U94

[24] Epigenetic Reprogramming in Plant and Animal Development [J].

Feng, Suhua ;

Jacobsen, Steven E. ;

Reik, Wolf .

SCIENCE, 2010, 330 (6004) :622-627

[25]

Foulds Charles E, 2010, Mol Endocrinol, V24, P1090, DOI 10.1210/me.2009-0427

[26] An oestrogen-receptor-α-bound human chromatin interactome [J].

Fullwood, Melissa J. ;

Liu, Mei Hui ;

Pan, You Fu ;

Liu, Jun ;

Xu, Han ;

Bin Mohamed, Yusoff ;

Orlov, Yuriy L. ;

Velkov, Stoyan ;

Ho, Andrea ;

Mei, Poh Huay ;

Chew, Elaine G. Y. ;

Huang, Phillips Yao Hui ;

Welboren, Willem-Jan ;

Han, Yuyuan ;

Ooi, Hong Sain ;

Ariyaratne, Pramila N. ;

Vega, Vinsensius B. ;

Luo, Yanquan ;

Tan, Peck Yean ;

Choy, Pei Ye ;

Wansa, K. D. Senali Abayratna ;

Zhao, Bing ;

Lim, Kar Sian ;

Leow, Shi Chi ;

Yow, Jit Sin ;

Joseph, Roy ;

Li, Haixia ;

Desai, Kartiki V. ;

Thomsen, Jane S. ;

Lee, Yew Kok ;

Karuturi, R. Krishna Murthy ;

Herve, Thoreau ;

Bourque, Guillaume ;

Stunnenberg, Hendrik G. ;

Ruan, Xiaoan ;

Cacheux-Rataboul, Valere ;

Sung, Wing-Kin ;

Liu, Edison T. ;

Wei, Chia-Lin ;

Cheung, Edwin ;

Ruan, Yijun .

NATURE, 2009, 462 (7269) :58-64

[27] Living without 30 nm chromatin fibers [J].

Fussner, Eden ;

Ching, Reagan W. ;

Bazett-Jones, David P. .

TRENDS IN BIOCHEMICAL SCIENCES, 2011, 36 (01) :1-6

[28] Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors [J].

Garcia-Bassets, Ivan ;

Kwon, Young-Soo ;

Telese, Francesca ;

Prefontaine, Gratien G. ;

Hutt, Kasey R. ;

Cheng, Christine S. ;

Ju, Bong-Gun ;

Ohgi, Kenneth A. ;

Wang, Jianxun ;

Escoubet-Lozach, Laure ;

Rose, David W. ;

Glass, Christopher K. ;

Fu, Xiang-Dong ;

Rosenfeld, Michael G. .

CELL, 2007, 128 (03) :505-518

[29] Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner [J].

Gertz, Jason ;

Reddy, Timothy E. ;

Varley, Katherine E. ;

Garabedian, Michael J. ;

Myers, Richard M. .

GENOME RESEARCH, 2012, 22 (11) :2153-2162

[30] Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis [J].

Gupta, Rajnish A. ;

Shah, Nilay ;

Wang, Kevin C. ;

Kim, Jeewon ;

Horlings, Hugo M. ;

Wong, David J. ;

Tsai, Miao-Chih ;

Hung, Tiffany ;

Argani, Pedram ;

Rinn, John L. ;

Wang, Yulei ;

Brzoska, Pius ;

Kong, Benjamin ;

Li, Rui ;

West, Robert B. ;

van de Vijver, Marc J. ;

Sukumar, Saraswati ;

Chang, Howard Y. .

NATURE, 2010, 464 (7291) :1071-U148

← 1 2 3 4 5 6 7 8 9 10 →