Selective androgen receptor modulators (SARMs): A novel approach to androgen therapy for the new millennium

被引：197

作者：

Negro-Vilar, A ^{[1
]}

机构：

[1] Ligand Pharmaceut Inc, San Diego, CA 92121 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1999年 / 84卷 / 10期

关键词：

D O I：

10.1210/jc.84.10.3459

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：3459 / 3462

页数：4

共 27 条

[11] New nonsteroidal androgen receptor modulators based on 4(trifluoromethyl)-2 (1H)-pyrrolidino[3,2-g] quinolinone [J].

Edwards, JP ;

West, SJ ;

Pooley, CLF ;

Marschke, KB ;

Farmer, LJ ;

Jones, TK .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (07) :745-750

[12]

ENSRUD K, 1998, BONE, V23, pS174

[13] CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1 [J].

Fronsdal, K ;

Engedal, N ;

Slagsvold, T ;

Saatcioglu, F .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (48) :31853-31859

[14] Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate [J].

Fujimoto, N ;

Yeh, SY ;

Kang, HY ;

Inui, S ;

Chang, HC ;

Mizokami, A ;

Chang, CS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (12) :8316-8321

[15] Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor [J].

Kang, HY ;

Yeh, SY ;

Fujimoto, N ;

Chang, CS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (13) :8570-8576

[16] Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones [J].

Katzenellenbogen, JA ;

OMalley, BW ;

Katzenellenbogen, BS .

MOLECULAR ENDOCRINOLOGY, 1996, 10 (02) :119-131

[17] ANALYSIS OF ESTROGEN-RECEPTOR FUNCTION IN-VITRO REVEALS 3 DISTINCT CLASSES OF ANTIESTROGENS [J].

MCDONNELL, DP ;

CLEMM, DL ;

HERMANN, T ;

GOLDMAN, ME ;

PIKE, JW .

MOLECULAR ENDOCRINOLOGY, 1995, 9 (06) :659-669

[18]

MEIKLE AW, 1998, TESTOSTERONE ACTION, P389

[19] EFFECTS OF ESTROGEN OR ESTROGEN/PROGESTIN REGIMENS ON HEART-DISEASE RISK-FACTORS IN POSTMENOPAUSAL WOMEN - THE POSTMENOPAUSAL ESTROGEN/PROGESTIN INTERVENTIONS (PEPI) TRIAL [J].

MILLER, VT ;

LAROSA, J ;

BARNABEI, V ;

KESSLER, C ;

LEVIN, G ;

SMITHROTH, A ;

GRIFFIN, M ;

STOY, DB ;

BUSH, T ;

ZACUR, H ;

FOSTER, D ;

ANDERSON, J ;

MCKENZIE, A ;

MILLER, S ;

WOOD, PD ;

STEFANICK, ML ;

MARCUS, R ;

AKANA, A ;

HEINRICHS, L ;

KIRCHNER, C ;

OHANLAN, K ;

RUYLE, M ;

SHEEHAN, M ;

JUDD, HL ;

GREENDALE, G ;

BAYALOS, R ;

LOZANO, K ;

KAWAKAMI, K ;

BARRETTCONNOR, E ;

LANGER, R ;

KRITZSILVERSTEIN, D ;

CARRIONPETERSEN, ML ;

CAVERO, C ;

SCHROTT, HG ;

JOHNSON, SR ;

FEDDERSEN, DA ;

KRUTZFELDT, DL ;

BENDA, JA ;

PAUERSTEIN, C ;

TRABAL, J ;

SCHENKEN, R ;

STERN, MP ;

RODRIGUEZSIFUENTES, M ;

EASTON, C ;

WELLS, HB ;

ESPELAND, M ;

HOWARD, G ;

BYINGTON, R ;

LEGAULT, C ;

SHUMAKER, S .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 273 (03) :199-208

[20] A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins [J].

Moilanen, AM ;

Karvonen, U ;

Poukka, H ;

Yan, W ;

Toppari, J ;

Jänne, OA ;

Palvimo, JJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (06) :3700-3704

← 1 2 3 →