Selective androgen receptor modulators (SARMs): A novel approach to androgen therapy for the new millennium

被引:197
作者
Negro-Vilar, A [1 ]
机构
[1] Ligand Pharmaceut Inc, San Diego, CA 92121 USA
关键词
D O I
10.1210/jc.84.10.3459
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:3459 / 3462
页数:4
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共 27 条
[21]   Identification characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPAR gamma 2 versus PPAR gamma 1 and activation with retinoid X receptor agonists and antagonists [J].
Mukherjee, R ;
Jow, L ;
Croston, GE ;
Paterniti, JR .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (12) :8071-8076
[22]  
Nieschlag E., 1998, TESTOSTERONE, P293, DOI [10.1007/978-3-642-72185-4_10, DOI 10.1007/978-3-642-72185-4_10]
[23]   OSTEOPOROSIS IN MEN [J].
ORWOLL, ES ;
KLEIN, RF .
ENDOCRINE REVIEWS, 1995, 16 (01) :87-116
[24]   Transactivation by retinoid X receptor peroxisome proliferator-activated receptor γ (PPARγ) heterodimers:: Intermolecular synergy requires only the PPARγ hormone-dependent activation function [J].
Schulman, IG ;
Shao, G ;
Heyman, RA .
MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (06) :3483-3494
[25]   Effect of testosterone treatment on bone mineral density in men over 65 years of age [J].
Snyder, PJ ;
Peachey, H ;
Hannoush, P ;
Berlin, JA ;
Loh, L ;
Holmes, JH ;
Dlewati, A ;
Staley, J ;
Santanna, J ;
Kapoor, SC ;
Attie, MF ;
Haddad, JG ;
Strom, BL .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (06) :1966-1972
[26]   5-aryl-1,2-dihydrochromeno[3,4-f]quinolines: A novel class of nonsteroidal human progesterone receptor agonists [J].
Zhi, L ;
Tegley, CM ;
Kallel, EA ;
Marschke, KB ;
Mais, DE ;
Gottardis, MM ;
Jones, TK .
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (03) :291-302
[27]   Switching androgen receptor antagonists to agonists by modifying C-ring substituents on piperidino[3,2-g]quinolinone [J].
Zhi, L ;
Tegley, CM ;
Marschke, KB ;
Jones, TK .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (07) :1009-1012