The power of VEGF (vascular endothelial growth factor) family molecules

被引:28
作者
Thomas, Jean-Leon [1 ,3 ,4 ,5 ]
Eichmann, Anne [2 ,6 ]
机构
[1] Yale Univ, Sch Med, Dept Neurol, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Dept Cardiol, New Haven, CT 06510 USA
[3] Univ Paris 06, Ctr Rech, Inst Cerveau & Moelle Epiniere, Paris, France
[4] INSERM, UMRS 975, Paris, France
[5] Grp Hosp Pitie Salpetriere, AP HP, F-75013 Paris, France
[6] Coll France, CNRS, Ctr Interdisciplinary Res Biol, INSERM,U1050,UMR 7241, F-75005 Paris, France
关键词
Vascular endothelial growth factors (VEGFs); Vascular endothelial growth factors receptors (VEGFRs); Angiogenesis; Neurogenesis; Neurovascular interactions; Brain diseases and disorders; ANGIOGENESIS;
D O I
10.1007/s00018-013-1276-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Vascular endothelial growth factors (VEGFs) and their high-affinity tyrosine kinase VEGF receptors (VEGFRs) are key regulators of both angiogenesis and neurogenesis. The current issue of CMLS discusses recent literature and work implementing these signals in nervous system development, maintenance and disease pathology.
引用
收藏
页码:1673 / 1674
页数:2
相关论文
共 10 条
[1]  
BREIER G, 1992, DEVELOPMENT, V114, P521
[2]   VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration [J].
Carmeliet, Peter ;
de Almodovar, Carmen Ruiz .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1763-1778
[3]   Navigation rules for vessels and neurons: cooperative signaling between VEGF and neural guidance cues [J].
Chauvet, Sophie ;
Burk, Katja ;
Mann, Fanny .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1685-1703
[4]   Vascular endothelial growth factors (VEGFs) and stroke [J].
Greenberg, David A. ;
Jin, Kunlin .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1753-1761
[5]   Delineating multiple functions of VEGF-A in the adult brain [J].
Licht, Tamar ;
Keshet, Eli .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1727-1737
[6]   Vascular growth factors in neuropsychiatry [J].
Newton, Samuel S. ;
Fournier, Neil M. ;
Duman, Ronald S. .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1739-1752
[7]   Neurovascular development and links to disease [J].
Ruhrberg, Christiana ;
Bautch, Victoria L. .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1675-1684
[8]   VASCULAR ENDOTHELIAL GROWTH-FACTOR INDUCED BY HYPOXIA MAY MEDIATE HYPOXIA-INITIATED ANGIOGENESIS [J].
SHWEIKI, D ;
ITIN, A ;
SOFFER, D ;
KESHET, E .
NATURE, 1992, 359 (6398) :843-845
[9]   Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind [J].
Wittko-Schneider, Ina M. ;
Schneider, Fabian T. ;
Plate, Karl H. .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2013, 70 (10) :1705-1725
[10]  
YANG K, 1996, J NEUROSCI, V16, P6089