Huntington's disease

被引:72
作者
Davies, S [1 ]
Ramsden, DB [1 ]
机构
[1] Univ Birmingham, Dept Med, Div Med Sci, Birmingham B15 2TH, W Midlands, England
来源
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY | 2001年 / 54卷 / 06期
关键词
Huntington's disease; neurodegenerative disorder; Huntingtin; NMDA receptors; kainate receptors;
D O I
10.1136/mp.54.6.409
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The most recent findings in the elucidation of the molecular pathology of Huntington's disease are reviewed. Particular interest has been paid to the role of huntingtin and its associated proteins in excitotoxicity mediated via NMDA and kainate receptors.
引用
收藏
页码:409 / 413
页数:5
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