Fecal microbiota transplantation for severe enterocolonic fistulizing Crohn's disease

被引：195

作者：

Zhang, Fa-Ming ^{[1
,2
]}

Wang, Hong-Gang ^{[1
,2
]}

Wang, Min ^{[1
,2
]}

Cui, Bo-Ta ^{[1
,2
]}

Fan, Zhi-Ning ^{[1
,2
]}

Ji, Guo-Zhong ^{[1
,2
]}

机构：

[1] Nanjing Med Univ, Nanjing 210011, Jiangsu, Peoples R China

[2] Nanjing Med Univ, Affiliated Hosp 2, Med Ctr Digest Dis, Nanjing 210011, Jiangsu, Peoples R China

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2013年 / 19卷 / 41期

关键词：

Fecal microbiota transplantation; Crohn's disease; Rescue therapy; Inflammatory bowel disease; Fistula; INFLAMMATORY-BOWEL-DISEASE; RECURRENT CLOSTRIDIUM-DIFFICILE; ULCERATIVE-COLITIS; MANAGEMENT; PREVENTION; DIAGNOSIS; FLORA;

D O I：

10.3748/wjg.v19.i41.7213

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

The concept of fecal microbiota transplantation (FMT) has been used in traditional Chinese medicine at least since the 4th century. Evidence from recent human studies strongly supports the link between intestinal bacteria and inflammatory bowel disease. We proposed that standardized FMT might be a promising rescue therapy for refractory inflammatory bowel disease. However, there were no reports of FMT used in patients with severe Crohn's disease (CD). Here, we report the successful treatment of standardized FMT as a rescue therapy for a case of refractory CD complicated with fistula, residual Barium sulfate and formation of intraperitoneal large inflammatory mass. As far as we know, this is the first case of severe CD treated using FMT through mid-gut. (C) 2013 Baishideng Publishing Group Co., Limited. All rights reserved.

引用

页码：7213 / 7216

页数：4

共 18 条

[1]

Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease [J].