Simple syntheses of cyclic polyamines using selectively N-tritylated polyamines and succinic anhydride

被引：14

作者：

Militsopoulou, M ^{[1
]}

Tsiakopoulos, N ^{[1
]}

Chochos, C ^{[1
]}

Magoulas, G ^{[1
]}

Papaioannou, D ^{[1
]}

机构：

[1] Univ Patras, Dept Chem, GR-26500 Patras, Greece

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 14期

关键词：

spermine; spermidine; cyclic anhydride; cyclic polyamine; trityl group;

D O I：

10.1016/S0040-4039(02)00335-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of selectively N-tritylated spermidine and spermine derivatives with succinic anhydride, followed by PyBrOP-mediated intramolecular amide bond formation and LiAlH4 reduction, allows for an easy and general entry to cyclic polyamine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.

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收藏

页码：2593 / 2596

页数：4

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