Early Experiences with Stem Cells in Treating Chronic Wounds

被引:67
作者
Akita, Sadanori [1 ]
Yoshimoto, Hiroshi [1 ]
Akino, Kozo [1 ]
Ohtsuru, Akira [2 ,3 ]
Hayashida, Kenji [1 ]
Hirano, Akiyoshi [1 ]
Suzuki, Keiji [4 ]
Yamashita, Shunichi [2 ,3 ,4 ]
机构
[1] Fukushima Med Univ, Dept Plast & Reconstruct Surg, Fukushima, Japan
[2] Fukushima Med Univ, Nagasaki Univ Hosp, Takashi Nagai Mem Int Hibakusha Med Ctr, Fukushima, Japan
[3] Fukushima Med Univ, Dept Radiat Hlth Management, Fukushima, Japan
[4] Nagasaki Univ, Sch Med, Atom Bomb Dis Inst, Nagasaki, Japan
基金
日本学术振兴会;
关键词
Nagasaki; Clinical study; Adipose-derived stem cell therapy for local chronic radiation injury; DIABETIC FOOT ULCERS; MARROW STROMAL CELLS; ADIPOSE-TISSUE; DERMAL MATRIX; IN-VIVO; THERAPY; SKIN; REPAIR; PROLIFERATION; DIFFERENTIATION;
D O I
10.1016/j.cps.2012.04.005
中图分类号
R61 [外科手术学];
学科分类号
100210 [外科学];
摘要
This review provides a thorough and clear discussion on the outcomes of stem cells in treating chronic wounds. With recent technological developments that now allow isolation and culture of stem cells, researchers are able to perform vigorous studies on somatic or adult stem cells. Human and animal stem cell studies are discussed with a focus on the basic process of stem cells in wound healing and the authors' first-hand clinical experience with stem cells used for chronic wound healing.
引用
收藏
页码:281 / +
页数:13
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