Modern developments in molecular replacement

被引：18

作者：

Turkenburg, JP

Dodson, EJ

机构：

[1] Chemistry Department, University of York, Heslington

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1996年 / 6卷 / 05期

关键词：

D O I：

10.1016/S0959-440X(96)80025-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular replacement is a possible route to obtaining initial phasing for an unknown structure from a known, structurally related molecule. Recent years have seen an explosive growth in the number of protein structures solved using this technique. Automated packages can make the application quite straightforward. Progress has been made in the placing of fragments of complexes, and in the use of imprecise models from NMR or homology modelling. Such models have necessitated the development of new approaches to rebuilding and refinement.

引用

收藏

页码：604 / 610

页数：7

相关论文

共 53 条

[1] THE USE OF PROTEIN HOMOLOGS IN THE ROTATION FUNCTION [J].

AGUILAR, CF ;

NEWMAN, MP ;

APARICIO, JS ;

COOPER, JB ;

TICKLE, IJ ;

BLUNDELL, TL .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 1993, 49 :306-315

[2] THE CCP4 SUITE - PROGRAMS FOR PROTEIN CRYSTALLOGRAPHY [J].

BAILEY, S .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1994, 50 :760-763

[3] USE OF IRON ANOMALOUS SCATTERING WITH MULTIPLE MODELS AND DATA SETS TO IDENTIFY AND REFINE A WEAK MOLECULAR REPLACEMENT SOLUTION - STRUCTURE-ANALYSIS OF CYTOCHROME-C' FROM 2 BACTERIAL SPECIES [J].

BAKER, EN ;

ANDERSON, BF ;

DOBBS, AJ ;

DODSON, EJ .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1995, 51 :282-289

[4] CRYSTAL-STRUCTURE OF INTERLEUKIN-8 - SYMBIOSIS OF NMR AND CRYSTALLOGRAPHY [J].

BALDWIN, ET ;

WEBER, IT ;

STCHARLES, R ;

XUAN, JC ;

APPELLA, E ;

YAMADA, M ;

MATSUSHIMA, K ;

EDWARDS, BFP ;

CLORE, GM ;

GRONENBORN, AM ;

WLODAWER, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (02) :502-506

[5] PROTEIN SECONDARY STRUCTURE PREDICTION [J].

BARTON, GJ .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1995, 5 (03) :372-376

[6]

BARTON GJ, 1992, MOL REPLACEMENT, P1

[7]

BLOW DM, 1985, MOL REPLACEMENT, P2

[8] ACETYLCHOLINESTERASE INHIBITION BY FASCICULIN - CRYSTAL-STRUCTURE OF THE COMPLEX [J].

BOURNE, Y ;

TAYLOR, P ;

MARCHOT, P .

CELL, 1995, 83 (03) :503-512

[9] SOLUTION OF A PROTEIN CRYSTAL-STRUCTURE WITH A MODEL OBTAINED FROM NMR INTERPROTON DISTANCE RESTRAINTS [J].

BRUNGER, AT ;

CAMPBELL, RL ;

CLORE, GM ;

GRONENBORN, AM ;

KARPLUS, M ;

PETSKO, GA ;

TEETER, MM .

SCIENCE, 1987, 235 (4792) :1049-1053

[10] EXTENSION OF MOLECULAR REPLACEMENT - A NEW SEARCH STRATEGY BASED ON PATTERSON CORRELATION REFINEMENT [J].

BRUNGER, AT .

ACTA CRYSTALLOGRAPHICA SECTION A, 1990, 46 :46-57

← 1 2 3 4 5 6 →