Risk factors for dengue virus infection in rural Amazonia:: Population-based cross-sectional surveys

被引：35

作者：

da Silva-Nunes, Monica ^{[1
]}

de Souza, Vanda A. F.

Pannuti, Claudio S.

Speranca, Marcia A.

Terzian, Ana Carolina B.

Nogueira, Mauricio L.

Yamamura, Anna M. Y.

Freire, Marcos S.

da Silva, Natal S.

Malafronte, Rosely S.

Muniz, Pascoal T.

Vasconcelos, Helena B.

da Silva, Eliana V. P.

Vasconcelos, Pedro F. C.

Ferreira, Marcelo U.

机构：

[1] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, BR-05508900 Sao Paulo, Brazil

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 79卷 / 04期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.4269/ajtmh.2008.79.485

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A comparison of dengue virus (DENV) antibody levels in paired serum samples collected from predominantly DENV-naive residents in an agricultural settlement in Brazilian Amazonia (baseline seroprevalence, 18.3%) showed a seroconversion rate of 3.67 episodes/100 person-years at risk during 12 months of follow-up. Multivariate analysis identified male sex, poverty, and migration from extra-Amazonian states as significant predictors of baseline DENY seropositivity, whereas male sex, a history of clinical diagnosis of dengue fever, and travel to an urban area predicted subsequent seroconversion. The laboratory surveillance of acute febrile illnesses implemented at the study site and in a nearby town between 2004 and 2006 confirmed 11. DENV infections among 102 episodes studied with DENV IgM detection, reverse transcriptase-polymerise chain reaction, and virus isolation; DENV-3 was isolated. Because DENV exposure is associated with migration or travel, personal protection measures when visiting high-risk urban areas may reduce the incidence of DENV infection in this rural population.

引用

页码：485 / 494

页数：10

共 43 条

[1] Molecular epidemiology of dengue type 3 virus in Brazil and Paraguay, 2002-2004 [J].

Aquino, Victor H. ;

Anatriello, Elen ;

Goncalves, Paula F. ;

da Silva, Eliana V. ;

Vasconcelos, Pedro F. C. ;

Vieira, Deusylene S. ;

Batista, Weber C. ;

Bobadilla, Maria L. ;

Vazquez, Cynthia ;

Moran, Mirian ;

Figueiredo, Luiz T. M. .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2006, 75 (04) :710-715

[2] Brazilian Flavivirus phylogeny based on NS5 [J].

Baleotti, FG ;

Moreli, ML ;

Figueiredo, LTM .

MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2003, 98 (03) :379-382

[3] High seroprevalence of antibodies against dengue virus in a prospective study of schoolchildren in Managua, Nicaragua [J].

Balmaseda, Angel ;

Hammond, Samantha N. ;

Tellez, Yolanda ;

Imhoff, Laurel ;

Rodriguez, Yoryelin ;

Saborio, Saira I. ;

Mercado, Juan C. ;

Perez, Leonel ;

Videa, Elsa ;

Almanza, Elvis ;

Kuan, Guillermina ;

Reyes, Miguel ;

Saenz, Leyla ;

Amador, Juan J. ;

Harris, Eva .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2006, 11 (06) :935-942

[4] Duplex reverse transcription-PCR followed by nested PCR assays for detection and identification of Brazilian Alphaviruses and Flaviviruses [J].

Bronzoni, RVD ;

Baleotti, FG ;

Nogueira, RMR ;

Nunes, M ;

Figueiredo, LTM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (02) :696-702

[5] Changing epidemiology of dengue hemorrhagic fever in Thailand [J].

Chareonsook, O ;

Foy, HM ;

Teeraratkul, A ;

Silarug, N .

EPIDEMIOLOGY AND INFECTION, 1999, 122 (01) :161-166

[6]

CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2

[7] Dengue epidemic in the State of Rio Grande do Norte, Brazil, in 1997 [J].

Cunha, RV ;

Schatzmayr, HG ;

Miagostovich, MP ;

Barbosa, AMA ;

Paiva, FG ;

Miranda, RMO ;

Ramos, CCF ;

Coelho, JCO ;

dos Santos, FB ;

Nogueira, RMR .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1999, 93 (03) :247-249

[8] Use of an immunoglobulin G avidity test to discriminate between primary and secondary dengue virus infections [J].

de Souza, VAUF ;

Fernandes, S ;

Araújo, ES ;

Tateno, AF ;

Oliveira, OMNPF ;

Oliveira, RD ;

Pannuti, CS .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (04) :1782-1784

[9]

DIETZ VJ, 1990, AM J EPIDEMIOL, V131, P693

[10] Spatial and temporal circulation of dengue virus serotypes: A prospective study of primary school children in Kamphaeng Phet, Thailand [J].

Endy, TP ;

Nisalak, A ;

Chunsuttiwat, S ;

Libraty, DH ;

Green, S ;

Rothman, AL ;

Vaughn, DW ;

Ennis, FA .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2002, 156 (01) :52-59

← 1 2 3 4 5 →