Synthesis and characterization of pH-responsive and fluorescent poly (amidoamine) dendrimer-grafted cellulose nanocrystals

被引：38

作者：

Chen, L. ^{[1
]}

Cao, W. ^{[1
]}

Grishkewich, N. ^{[1
]}

Berry, R. M. ^{[2
]}

Tam, K. C. ^{[1
]}

机构：

[1] Univ Waterloo, Waterloo Inst Nanotechnol, Dept Chem Engn, Waterloo, ON N2L 3G1, Canada

[2] CelluForce Inc, Montreal, PQ H3A 1K2, Canada

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2015年 / 450卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

Cellulose nanocrystals; Poly (amidoamine) dendrimer; Fluorescence; pH responsive; Surfactant interactions; PAMAM DENDRIMERS; OXIDE NANOPARTICLES; DRUG-DELIVERY; EMISSION; CHARGE;

D O I：

10.1016/j.jcis.2015.03.002

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Poly (amidoamine) (PAMAM) dendrimers have found promising applications in biomedicine and in the encapsulation of inorganic nanoparticles. G6 PAMAM dendrimer-grafted cellulose nanocrystals (CNC-PAMAM) were prepared via a simple carbodiimide-mediated amidation process and they displayed pH-responsive and fluorescent characteristics as confirmed by zeta potential, transmittance, isothermal titration calorimetry (ITC), and fluorescence spectroscopy. Stable aqueous dispersions of CNC-PAMAM were obtained at pH <= 4 and pH >= 10, driven by electrostatic repulsion from positive charge and negative charge respectively. However, large aggregates were formed at pH values from 5 to 9 due to electrostatic attraction. In addition, strong blue fluorescent emission was observed, and the fluorescent behaviour of CNC-PAMAM was influenced by the formation of aggregates. The pH-responsive and fluorescent properties of CNC-PAMAM may be suitable for their applications in pH-responsive nanodevices, fluorescent-based pH sensors, optical markers, and nanoreactors for the encapsulation of inorganic nanoparticles. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：101 / 108

页数：8

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