Synthesis of some N-[1-alkyl(aryl)3-oxo-4,4,4-trichloro(trifluoro)-1-buten-1-yl]-o-aminophenols and o-phenylenediamines as potential anticancer agents

被引:22
作者
Bonacorso, HG [1 ]
Wentz, AP [1 ]
Bittencourt, SRT [1 ]
Marques, LML [1 ]
Zanatta, N [1 ]
Martins, MAP [1 ]
机构
[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil
关键词
D O I
10.1081/SCC-120002116
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of a novel series of N-[1-alkyl(aryl)-3-oxo-4,4,4-trichloro(trifluoro)-1-buten-1-yl]-o-aminophenols and the analogous o-phenylenediamine derivatives [X3CC(O) CH=CR(o-NHC(6)H(4)y), where X=F, Cl; R=H, Me, Et, aryl; and Y = NH2, OH] is reported.
引用
收藏
页码:335 / 341
页数:7
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