A Switchable Biocompatible Polymer Surface with Self-Sterilizing and Nonfouling Capabilities

被引：330

作者：

Cheng, Gang ^{[1
]}

Xite, Hong ^{[1
]}

Zhang, Zheng ^{[1
]}

Chen, Shengfu ^{[1
]}

Jiang, Shaoyi ^{[1
]}

机构：

[1] Univ Washington, Dept Chem Engn, Seattle, WA 98195 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 46期

关键词：

antimicrobial activity; nonfouling coatings; polymerization; surface chemistry; zwitterions;

D O I：

10.1002/anie.200803570

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Trap, kill, and release: An antimicrobial cationic surface can effectively kill bacterial cells and switch to a nonfouling zwitterionic surface which releases dead microorganisms upon hydrolysis (see picture). This biocompatible nonfouling surface can prevent further attachment of proteins and microorganisms and the formation of a biofilm on the surface. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：8831 / 8834

页数：4

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