Stem cells for spinal cord repair

被引：228

作者：

Barnabe-Heider, Fanie ^{[1
]}

Frisen, Jonas ^{[1
]}

机构：

[1] Karolinska Inst, Dept Cell & Mol Biol, Med Nobel Inst, SE-17177 Stockholm, Sweden

来源：

CELL STEM CELL | 2008年 / 3卷 / 01期

关键词：

D O I：

10.1016/j.stem.2008.06.011

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Spinal cord injury typically results in permanent disability. Many studies have indicated that transplantation of several different types of stem cells promotes functional recovery in animal models of spinal cord injury. A conceptually different approach to utilize stem cells for regenerative therapies may be recruitment of endogenous neural stem cells resident in the adult spinal cord. We discuss the possibilities, risks, and mechanisms for stem cells in spinal cord repair.

引用

页码：16 / 24

页数：9

共 74 条

[1] Targeting recovery: Priorities of the spinal cord-injured population [J].

Anderson, KD .

JOURNAL OF NEUROTRAUMA, 2004, 21 (10) :1371-1383

[2] Update on the treatment of spinal cord injury [J].

Baptiste, Darryl C. ;

Fehlings, Michael G. .

NEUROTRAUMA: NEW INSIGHTS INTO PATHOLOGY AND TREATMENT, 2007, 161 :217-233

[3] SUPPRESSION OF REMYELINATION IN CNS BY X-IRRADIATION [J].

BLAKEMORE, WF ;

PATTERSON, RC .

ACTA NEUROPATHOLOGICA, 1978, 42 (02) :105-113

[4] Everything that glitters isn't gold: A critical review of postnatal neural precursor analyses [J].

Breunig, Joshua J. ;

Arellano, Jon I. ;

Macklis, Jeffrey D. ;

Rakic, Pasko .

CELL STEM CELL, 2007, 1 (06) :612-627

[5] Embryonic stem cell-derived glial precursors:: A source of myelinating transplants [J].

Brüstle, O ;

Jones, KN ;

Learish, RD ;

Karram, K ;

Choudhary, K ;

Wiestler, OD ;

Duncan, ID ;

McKay, RDG .

SCIENCE, 1999, 285 (5428) :754-756

[6] The role of extracellular matrix in CNS regeneration [J].

Busch, Sarah A. ;

Silver, Jerry .

CURRENT OPINION IN NEUROBIOLOGY, 2007, 17 (01) :120-127

[7] Delivery of autologous bone marrow precursor cells into the spinal cord via lumbar puncture technique in patients with spinal cord injury: A preliminary safety study [J].

Callera, F ;

do Nascimento, RX .

EXPERIMENTAL HEMATOLOGY, 2006, 34 (02) :130-131

[8] Genetic visualization of neurogenesis [J].

Carlen, Marie ;

Meletis, Konstantinos ;

Barnabe-Heider, Fanie ;

Frisen, Jonas .

EXPERIMENTAL CELL RESEARCH, 2006, 312 (15) :2851-2859

[9] Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? [J].

Courtine, Gregoire ;

Bunge, Mary Bartlett ;

Fawcett, James W. ;

Grossman, Robert G. ;

Kaas, Jon H. ;

Lemon, Roger ;

Maier, Irin ;

Martin, John ;

Nudo, Randolph J. ;

Ramon-Cueto, Almudena ;

Rouiller, Eric M. ;

Schnell, Lisa ;

Wannier, Thierry ;

Schwab, Martin E. ;

Edgerton, V. Reggie .

NATURE MEDICINE, 2007, 13 (05) :561-566

[10] Chinese network to start trials of spinal surgery [J].

Cyranoski, David .

NATURE, 2007, 446 (7135) :476-477

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