Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?

被引:295
作者
Courtine, Gregoire
Bunge, Mary Bartlett
Fawcett, James W.
Grossman, Robert G.
Kaas, Jon H.
Lemon, Roger
Maier, Irin
Martin, John
Nudo, Randolph J.
Ramon-Cueto, Almudena
Rouiller, Eric M.
Schnell, Lisa
Wannier, Thierry
Schwab, Martin E.
Edgerton, V. Reggie [1 ]
机构
[1] Univ Calif Los Angeles, Dept Physiol Sci & Neurobiol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Brain Res Inst, Los Angeles, CA 90095 USA
[3] Univ Miami, Sch Med, Miami Project Cure Paralysis, Dept Cell Biol & Anat, Miami, FL 33101 USA
[4] Univ Miami, Sch Med, Dept Neurol Surg, Miami, FL 33101 USA
[5] Univ Cambridge, Brain Repair Ctr, Cambridge CB2 2PY, England
[6] Methodist Hosp, Inst Neurol, Dept Neurosurg, Houston, TX 77030 USA
[7] Vanderbilt Univ, Dept Psychol, Nashville, TN 37203 USA
[8] UCL, Inst Neurol, London WC1N 3BG, England
[9] Univ Zurich, Brain Res Inst, CH-8057 Zurich, Switzerland
[10] Columbia Univ, Ctr Neurobiol & Behav, New York, NY 10032 USA
[11] Univ Kansas, Med Ctr, Landon Ctr Aging, Dept Mol & Integrat Physiol, Kansas City, KS 66160 USA
[12] Spanish Council Sci Res, Lab Neural Regenerat, Inst Biomed, Valencia 46010, Spain
[13] Univ Fribourg, Inst Physiol, CH-1700 Fribourg, Switzerland
关键词
D O I
10.1038/nm1595
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
引用
收藏
页码:561 / 566
页数:6
相关论文
共 31 条
[1]
A global perspective on spinal cord injury epidemiology [J].
Ackery, A ;
Tator, C ;
Krassioukov, A .
JOURNAL OF NEUROTRAUMA, 2004, 21 (10) :1355-1370
[2]
Targeting recovery: Priorities of the spinal cord-injured population [J].
Anderson, KD .
JOURNAL OF NEUROTRAUMA, 2004, 21 (10) :1371-1383
[3]
Magnetic brain stimulation can improve clinical outcome in incomplete spinal cord injured patients [J].
Belci, M ;
Catley, M ;
Husain, M ;
Frankel, HL ;
Davey, NJ .
SPINAL CORD, 2004, 42 (07) :417-419
[4]
CORTICOSPINAL TERMINATIONS IN 2 NEW-WORLD PRIMATES - FURTHER EVIDENCE THAT CORTICOMOTONEURONAL CONNECTIONS PROVIDE PART OF THE NEURAL SUBSTRATE FOR MANUAL DEXTERITY [J].
BORTOFF, GA ;
STRICK, PL .
JOURNAL OF NEUROSCIENCE, 1993, 13 (12) :5105-5118
[5]
Performance of locomotion and foot grasping following a unilateral thoracic corticospinal tract lesion in monkeys (Macaca mulatta) [J].
Courtine, G ;
Roy, RR ;
Raven, J ;
Hodgson, J ;
Mckay, H ;
Yang, H ;
Zhong, H ;
Tuszynski, MH ;
Edgerton, VR .
BRAIN, 2005, 128 :2338-2358
[6]
Extensive cortical rewiring after brain injury [J].
Dancause, N ;
Barbay, S ;
Frost, SB ;
Plautz, EJ ;
Chen, DF ;
Zoubina, EV ;
Stowe, AM ;
Nudo, RJ .
JOURNAL OF NEUROSCIENCE, 2005, 25 (44) :10167-10179
[7]
Loss and recovery of voluntary hand movements in the macaque following a cervical dorsal rhizotomy [J].
Darian-Smith, C ;
Ciferri, MM .
JOURNAL OF COMPARATIVE NEUROLOGY, 2005, 491 (01) :27-45
[8]
Repair of spinal cord injuries: where are we, where are we going? [J].
Fawcett, J .
SPINAL CORD, 2002, 40 (12) :615-623
[9]
Regenerating corticospinal fibers in the Marmoset (Callitrix jacchus) after spinal cord lesion and treatment with the anti-Nogo-A antibody IN-1 [J].
Fouad, K ;
Klusman, I ;
Schwab, ME .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2004, 20 (09) :2479-2482
[10]
Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates [J].
Freund, Patrick ;
Schmidlin, Eric ;
Wannier, Thierry ;
Bloch, Jocelyne ;
Mir, Anis ;
Schwab, Martin E. ;
Rouiller, Eric M. .
NATURE MEDICINE, 2006, 12 (07) :790-792