Update on antimicrobial susceptibility trends among Streptococcus pneumoniae in the United States: report of ceftaroline activity from the SENTRY Antimicrobial Surveillance Program (1998-2011)

被引：70

作者：

Jones, Ronald N. ^{[1
]}

Sader, Helio S. ^{[1
]}

Mendes, Rodrigo E. ^{[1
]}

Flamm, Robert K. ^{[1
]}

机构：

[1] JMI Labs, N Liberty, IA 52317 USA

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2013年 / 75卷 / 01期

关键词：

S; pneumoniae; Resistance; Ceftaroline; Vaccines;

D O I：

10.1016/j.diagmicrobio.2012.08.024

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A 14-year longitudinal survey of Streptococcus pneumoniae (18,911) strains by the SENTRY Antimicrobial Surveillance Program shows significant increases in resistance to amoxicillin/clavulanate (18.9%), penicillin at a MIC of >= 4 mu g/mL (14.8%), and ceftriaxone (11.7%) among 2011 isolates. Fluoroquinolones (levofloxacin; 98.8% susceptible) and ceftaroline (99.1-100.0% susceptible depending on breakpoint criteria) exhibited high levels of potency, as did linezolid, tigecycline, and vancomycin (100.0%). In summary, resistance rates to several antimicrobials continue to rise after introductions of both pneumococcal conjugate vaccines, as noted from these results for 1998 through 2011. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：107 / 109

页数：3

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