Structural Analysis of Synthetic Polymer Mixtures Using Ion Mobility and Tandem Mass Spectrometry

被引：58

作者：

Hilton, Gillian R. ^{[2
]}

Jackson, Anthony T. ^{[1
]}

Thalassinos, Konstantinos ^{[2
]}

Scrivens, James H. ^{[2
]}

机构：

[1] AkzoNobel China Appl Res Grp, Shanghai 201600, Peoples R China

[2] Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England

来源：

ANALYTICAL CHEMISTRY | 2008年 / 80卷 / 24期

关键词：

D O I：

10.1021/ac801716c

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Ion mobility (IM) combined with tandem mass spectrometry (MS/MS) has been employed to separate and differentiate between polyether oligomers with the same nominal molecular weights. Poly(ethylene glycol)s with the same nominal mass-to-charge ratio (m/z), but with differing structures, were separated using ion mobility. IMMS/MS data were able to aid identification of the backbone and end groups of the four individual polyethers in the two sets of isobaric mixtures. The MS/MS data from the resolved oligomers enabled a detailed structural characterization of the polyether mixtures to be completed in one experiment.

引用

页码：9720 / 9725

页数：6

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