Iodine catalyzed conjugate addition of mercaptans to α,β-unsaturated carboxylic acids under solvent-free condition

被引：58

作者：

Gao, SJ ^{[1
]}

Tzeng, TK ^{[1
]}

Sastry, MNV ^{[1
]}

Chu, CM ^{[1
]}

Liu, JT ^{[1
]}

Lin, CC ^{[1
]}

Yao, CF ^{[1
]}

机构：

[1] Natl Taiwan Normal Univ, Dept Chem, Taipei 116, Taiwan

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 12期

关键词：

conjugate addition; thiols; alpha; beta-unsaturated carboxylic acid; iodine; solvent free;

D O I：

10.1016/j.tetlet.2006.01.080

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have described herein molecular iodine catalyzed Michael addition of thiol to alpha,beta-unsaturated carboxylic acids. This environmentally benign catalytic system (iodine) used under mild and solvent-free conditions to achieve the corresponding adducts in excellent yield. (c) 2006 Published by Elsevier Ltd.

引用

收藏

页码：1889 / 1893

页数：5

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