Benign and highly efficient synthesis of quinolines from 2-aminoarylketone or 2-aminoarylaldehyde and carbonyl compounds mediated by hydrochloric acid in water

被引：118

作者：

Wang, GW ^{[1
]}

Jia, CS

Dong, YW

机构：

[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 07期

基金：

中国国家自然科学基金;

关键词：

quinolines; Friedlander reaction; aqueous reaction;

D O I：

10.1016/j.tetlet.2005.12.053

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An environmentally friendly and highly efficient procedure for the preparation Of substituted quinoline derivatives was developed by a simple Friedlander reaction of 2-aminoarylketone or 2-aminoarylaldehyde with carbonyl compounds in the presence of hydrochloric acid utilizing water as the solvent. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1059 / 1063

页数：5

共 57 条

[1] Fused quinolines. Recent synthetic approaches to azoloquinolines. A review [J].