A simple, efficient and solvent-free protocol for the Friedlander synthesis of quinolines by using SnCl2 • 2H2O

被引:74
作者
Arumugam, P [1 ]
Karthikeyan, G [1 ]
Atchudan, R [1 ]
Muralidharan, D [1 ]
Perumal, PT [1 ]
机构
[1] Cent Leather Res Inst, Div Organ Chem, Madras 20, Tamil Nadu, India
关键词
D O I
10.1246/cl.2005.314
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A variety of polysubstituted quinolines have been synthesized under solvent free condition by using tin(II) chloride-dihydrate. The reaction proceeds smoothly at room temperature in short reaction time. The yields and purity are excellent.
引用
收藏
页码:314 / 315
页数:2
相关论文
共 15 条
  • [1] A new green approach to the Friedlander synthesis of quinolines
    Arcadi, A
    Chiarini, M
    Di Giuseppe, S
    Marinelli, F
    [J]. SYNLETT, 2003, (02) : 203 - 206
  • [2] Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction
    Bi, YZ
    Stoy, P
    Adam, L
    He, B
    Krupinski, J
    Normandin, D
    Pongrac, R
    Seliger, L
    Watson, A
    Macor, JE
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (06) : 1577 - 1580
  • [3] A synthesis of camptothecin
    Chavan, SP
    Sivappa, R
    [J]. TETRAHEDRON LETTERS, 2004, 45 (15) : 3113 - 3115
  • [4] Synthesis and antibacterial evaluation of certain quinolone derivatives
    Chen, YL
    Fang, KC
    Sheu, JY
    Hsu, SL
    Tzeng, CC
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (14) : 2374 - 2377
  • [5] Quinolines as potent 5-lipoxygenase inhibitors:: Synthesis and biological profile of L-746,530
    Dubé, D
    Blouin, M
    Brideau, C
    Chan, CC
    Desmarais, S
    Ethier, D
    Falgueyret, JP
    Friesen, RW
    Girard, M
    Girard, Y
    Guay, J
    Riendeau, D
    Tagari, P
    Young, RN
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (10) : 1255 - 1260
  • [7] Synthesis and pharmacological properties of some quinoline derivatives
    Kalluraya, B
    Sreenivasa, S
    [J]. FARMACO, 1998, 53 (06): : 399 - 404
  • [8] KEMPTER G, 1996, PRAKT CHEMIE, V34, P298
  • [9] Practical route to a new class of LTD(4) receptor antagonists
    Larsen, RD
    Corley, EG
    King, AO
    Carroll, JD
    Davis, P
    Verhoeven, TR
    Reider, PJ
    Labelle, M
    Gauthier, JY
    Xiang, YB
    Zamboni, RJ
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (10) : 3398 - 3405
  • [10] A mild and efficient one-step synthesis of quinolines
    McNaughton, BR
    Miller, BL
    [J]. ORGANIC LETTERS, 2003, 5 (23) : 4257 - 4259