Carbon nanotube/gold nanoparticles/polyethylenimine-functionalized ionic liquid thin film composites for glucose biosensing

被引：128

作者：

Jia, Fei ^{[1
]}

Shan, Changsheng ^{[1
]}

Li, Fenghua ^{[1
]}

Niu, Li ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China

[2] Abo Akad Univ, Analyt Chem Lab, FIN-2050 Turku, Finland

来源：

BIOSENSORS & BIOELECTRONICS | 2008年 / 24卷 / 04期

关键词：

Ionic liquids; Carbon nanotubes; Gold nanoparticles; Glucose oxidase; Biosensing;

D O I：

10.1016/j.bios.2008.07.057

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A novel glucose biosensor based on immobilization of glucose oxidase (GOD) in thin films of polyethylenimine-functionalized ionic liquid (PFIL), containing a mixture of carbon nanotubes (CNT) and gold nanoparticles (AuNPs) and deposited on glassy carbon electrodes, was developed. Direct electrochemistry of glucose oxidase in the film was observed, with linear glucose response up to 12 mM. The PFIL-stabilized gold nanoparticles had a diameter of 2.4 +/- 0.8 nm and exhibited favorable stability (stored even over one month with invisible change in UV-vis spectroscopic measurements). In addition, CNT were also well dispersed in the PFIL matrix, then, the resulting CNT/AuNPs/PFIL composites film showed high electrocatalytic activity toward reduction of hydrogen peroxide and oxygen. Here, PFIL, due to its high ionic conductivity, good solubility to CNT, and stability to nanoparticles, played an important role in constructing stable CNT/AuNPs/PFIL/GOD composites. And good biocompatibility of PFIL also offered a friendly environment for the immobilization of biomolecules. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：945 / 950

页数：6

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