High yielding microwave-assisted synthesis of tri-substituted 1,3,5-triazines using Pd-catalyzed aryl and heteroarylamination

被引：20

作者：

Dao, Pascal ^{[1
]}

Garbay, Christiane ^{[1
]}

Chen, Huixiong ^{[1
]}

机构：

[1] Univ Paris 05, Lab Chim & Biochim Pharmacol & Toxicol, UMR 8601, UFR Biomed, F-75270 Paris 06, France

来源：

TETRAHEDRON | 2012年 / 68卷 / 20期

关键词：

Synthesis; Microwave chemistry; Cross-coupling reactions; Triazines; Rotamers; TRIAZINES;

D O I：

10.1016/j.tet.2012.03.041

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

A rapid and efficient Pd-catalyzed aryl and heteroarylamination under microwave irradiation has been developed for various tri-substituted triazines that can serve as versatile building blocks for both supramolecular and medicinal chemistry research. Particularly valuable features of this method included the short reaction time, good yield, and convenient operation. (C) 2012 Elsevier Ltd. All rights reserved.

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收藏

页码：3856 / 3860

页数：5

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