A direct organocatalytic entry to sphingoids:: asymmetric synthesis of D-arabino- and L-ribo-phytosphingosine

被引：82

作者：

Enders, D ^{[1
]}

Palecek, J ^{[1
]}

Grondal, C ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 06期

关键词：

D O I：

10.1039/b515007h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The organocatalytic asymmetric synthesis of D-arabino- and L-ribo-phytosphingosine is described employing a diastereo-and enantioselective (S)-proline-catalyzed aldol reaction of 2,2-dimethyl-1,3-dioxan-5-one and pentadecanal as the key step.

引用

页码：655 / 657

页数：3

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