Efficient homogeneous catalytic hydrogenation of esters to alcohols

被引：490

作者：

Zhang, J

Leitus, G

Ben-David, Y

Milstein, D ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel

[2] Weizmann Inst Sci, Chem Res Support, IL-76100 Rehovot, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 07期

关键词：

alcohols; esters; homogeneous catalysis; hydrogenation; ruthenium;

D O I：

10.1002/anie.200503771

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) With open arms: A ruthenium PNN complex (see scheme) catalyzes the hydrogenation of esters in high yields under neutral conditions. The analogous PNP complex is less active. A mechanism is proposed based on the hemilabile nature of the PNN ligand which allows a vacant site to be created by decoordination of the -CH2NEt2 arm. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：1113 / 1115

页数：3

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