Electrostatic placement of single ferritin molecules

被引:70
作者
Kumagai, S
Yoshii, S
Yamada, K
Matsukawa, N
Fujiwara, I
Iwahori, K
Yamashita, I
机构
[1] Matsushita Elect Ind Co Ltd, ARTL, Kyoto 6190237, Japan
[2] Nara Inst Adv Sci & Technol, Grad Sch Mat Sci, Ikoma, Nara 6300101, Japan
[3] Japan Sci & Technol Agcy, CREST, Kawaguchi, Saitama 3320012, Japan
关键词
D O I
10.1063/1.2189566
中图分类号
O59 [应用物理学];
学科分类号
摘要
We electrostatically placed a single ferritin molecule on a nanometric 3-aminopropyltriethoxysilane (APTES) pattern that was on an oxidized Si substrate. The numerical analysis of the total interaction free energy for ferritin predicted that a quadrilateral array of 15 nm diameter APTES nanodisks placed at intervals of 100 nm would accommodate a single molecule of ferritin in each disk under a Debye length of 14 nm. The experiments we conducted conformed to theoretical predictions and we successfully placed a single ferritin molecule on each ATPES disk without ferritin adsorbing on the SiO2 substrate surface.
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页数:3
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