Genetic control of Aedes mosquitoes

被引:96
作者
Alphey, Luke [1 ,2 ]
McKemey, Andrew [1 ]
Nimmo, Derric [1 ]
Neira Oviedo, Marco [1 ,3 ]
Lacroix, Renaud [1 ]
Matzen, Kelly [1 ]
Beech, Camilla [1 ]
机构
[1] Oxitec Ltd, Oxford OX14 4RX, England
[2] Univ Oxford, Dept Zool, Oxford OX1 3PS, England
[3] Pontificia Univ Catolica Ecuador, Ctr Infect Dis Res, Quito, Ecuador
关键词
Aedes; Genetic engineering; RIDL; SIT; IIT; Wolbachia; Dengue; YELLOW-FEVER MOSQUITO; ANOPHELES-ARABIENSIS MOSQUITOS; DENGUE VIRUS; ENGINEERED UNDERDOMINANCE; MATING COMPETITIVENESS; WOLBACHIA-PIPIENTIS; GLOBAL DISTRIBUTION; DIPTERA-CULICIDAE; FIELD PERFORMANCE; FEEDING PATTERNS;
D O I
10.1179/2047773213Y.0000000095
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Aedes mosquitoes include important vector species such as Aedes aegypti, the major vector of dengue. Genetic control methods are being developed for several of these species, stimulated by an urgent need owing to the poor effectiveness of current methods combined with an increase in chemical pesticide resistance. In this review we discuss the various genetic strategies that have been proposed, their present status, and future prospects. We focus particularly on those methods that are already being tested in the field, including RIDL and Wolbachia-based approaches.
引用
收藏
页码:170 / 179
页数:10
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