New evidence on variations of human body burden of methylmercury from fish consumption

被引:86
作者
Canuel, R
de Grosbois, SB
Atikessé, L
Lucotte, M
Arp, P
Ritchie, C
Mergler, D
Chan, HM
Amyot, M
Anderson, R
机构
[1] Univ Quebec, COMERN, Inst Environm Sci, Montreal, PQ H3C 3P8, Canada
[2] Univ Quebec, CINBIOSE, Collaborat Mercury Res Network, Montreal, PQ H3C 3P8, Canada
[3] Univ New Brunswick, Collaborat Mercury Res Network, Fac Forestry & Environm Management, Fredericton, NB E3B 5A3, Canada
[4] McGill Univ, Collaborat Mercury Res Network, Ctr Indigenous Peoples Nutr & Environm, Ste Anne De Bellevue, PQ, Canada
[5] Univ Montreal, Dept Biol, Collaborat Mercury Res Network, Montreal, PQ H3C 3J7, Canada
[6] Dept Fisheries & Oceans Canada, Collaborat Mercury Res Network, St John, NF, Canada
关键词
First Nations communities; fish consumption; hair mercury levels; human metabolism; methylmercury;
D O I
10.1289/ehp.7857
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Epidemiologic studies commonly use mercury (Hg) level in hair as a valid proxy to estimate human exposure to methylimercury (MeHg) through fish consumption. This study presents the results yielded by a complete data set on fish consumption habits, Hg levels in edible fish resources, and corresponding Hg accumulation in hair, gathered in three distinct communities of eastern Canada. For one of these communities, the average hair Hg concentration was 14 times less than the expected value based on calculated daily oral exposure and current knowledge of MeHg metabolism. This finding could be explained by differences in specific genetic characteristics and/or interactive effects of other dietary components.
引用
收藏
页码:302 / 306
页数:5
相关论文
共 38 条
[21]  
Lebel J, 1997, WATER AIR SOIL POLL, V97, P31, DOI 10.1023/A:1018378207932
[22]  
McPherson R. Sue, 1995, Annals of Epidemiology, V5, P378, DOI 10.1016/1047-2797(95)00035-6
[23]   Total mercury intake from fish and shellfish by Japanese people [J].
Nakagawa, R ;
Yumita, Y ;
Hiromoto, M .
CHEMOSPHERE, 1997, 35 (12) :2909-2913
[24]   Methods and rationale for derivation of a reference dose for methylmercury by the US EPA [J].
Rice, DC ;
Schoeny, R ;
Mahaffey, K .
RISK ANALYSIS, 2003, 23 (01) :107-115
[25]   Reliability and relative validity of fish consumption data obtained in an exposure assessment study among Montreal-area sportfishers [J].
Shatenstein, B ;
Kosatsky, T ;
Nadon, S ;
Lussier-Cacan, S ;
Weber, JP .
ENVIRONMENTAL RESEARCH, 1999, 80 (02) :S71-S86
[26]   ELEVATION OF MERCURY IN HUMAN-BLOOD FROM CONTROLLED CHRONIC INGESTION OF METHYLMERCURY IN FISH [J].
SHERLOCK, J ;
HISLOP, J ;
NEWTON, D ;
TOPPING, G ;
WHITTLE, K .
HUMAN TOXICOLOGY, 1984, 3 (02) :117-131
[27]   Glutathione S-transferase: genetics and role in toxicology [J].
Strange, RC ;
Jones, PW ;
Fryer, AA .
TOXICOLOGY LETTERS, 2000, 112 :357-363
[28]  
Tremblay A., 1999, MERCURY BIOGEOCHEMIC, P235
[29]   The use of polynomial regression analysis with indicator variables for interpretation of mercury in fish data [J].
Tremblay, G ;
Legendre, P ;
Doyon, JF ;
Verdon, R ;
Schetagne, R .
BIOGEOCHEMISTRY, 1998, 40 (2-3) :189-201
[30]  
*US EPA, 1987, MERC STUD REP C