Solvent-free synthesis of racemic cyanohydrin O-phosphates

被引：18

作者：

Baeza, A

Nájera, C

Sansano, JM

机构：

[1] Univ Alicante, Fac Ciencias, Dept Quim Organ, Apdo 99, E-03080 Alicante, Spain

[2] Univ Alicante, ISO, E-03080 Alicante, Spain

来源：

ARKIVOC | 2005年

关键词：

Green chemistry; aldehydes; ketones; catalysis; cyanohydrin derivatives; cyanophosphates;

D O I：

10.3998/ark.5550190.0006.930

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aldehydes and ketones are transformed into racemic cyanohydrin O-phosphates by reaction with stoichiometric amounts of diethyl cyanophosphonate and sub-stoichiometric amounts of triethylamine (10 mol. %), at room temperature in the absence of solvent. This green process takes place in excellent yield and with very short reaction time.

引用

收藏

页码：353 / 363

页数：11

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