ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death

被引:121
作者
Zhaorigetu, Siqin [1 ]
Wan, Guanghua [1 ]
Kaini, Ramesh [1 ]
Jiang, Zeyu [1 ]
Hu, Chien-an A. [1 ]
机构
[1] Univ New Mexico, Sch Med, Dept Biochem & Mol Biol, Albuquerque, NM 87131 USA
关键词
trypanosomal lytic factor; apolipoprotein L1 (ApoL1); autophagy; autophagic cell death; BH3-only protein; cardiolipin; lipid binding; PIPs; phosphatidic acid; schizophrenia; SNPs;
D O I
10.4161/auto.7066
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Abbreviations: ANTH, AP180/CALM; ACD, aurophagic cell death; AV, autophagic vacuoles; BH, Bcl-2 homology domain; CL, cardiolipin; ENTH, epsin N-terminal homology; FEPM, band4.1, ezrin, radixin and moesin; FYVE, Fablp, YOTB, Vaclp and EEAl; GRAM, glucosyltransferase, Rab-like GTPase activator and myotbularins; LC3, microtubule associated proteins light chain 3; 3-MA, 3-methyladenine; PA, phosphatidic acid; PH, pleckstrin homology; PI, phosphatidylinositol; PI3K, phosphatidylinositol-3-phosphate kinase; PIPs, phosphoinositides; PX, phox homology; PCD, programmed cell death; SNP single nucleotide polymorphism
引用
收藏
页码:1079 / 1082
页数:4
相关论文
共 30 条
[1]   Phosphatidic acid-mediated mitogenic activation of mTOR signaling [J].
Fang, YM ;
Vilella-Bach, M ;
Bachmann, R ;
Flanigan, A ;
Chen, J .
SCIENCE, 2001, 294 (5548) :1942-1945
[2]   Cardiolipin: Setting the beat of apoptosis [J].
Gonzalvez, Francois ;
Gottlieb, Eyal .
APOPTOSIS, 2007, 12 (05) :877-885
[3]   Reversible membrane interaction of BAD requires two C-terminal lipid binding domains in conjunction with 14-3-3 protein binding [J].
Hekman, Mirko ;
Albert, Stefan ;
Galmiche, Antoine ;
Rennefahrt, Ulrike E. E. ;
Fueller, Jochen ;
Fischer, Andreas ;
Puehringer, Dirk ;
Wiese, Stefan ;
Rapp, Ulf R. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (25) :17321-17336
[4]   The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle [J].
Hornberger, TA ;
Chu, WK ;
Mak, YW ;
Hsiung, JW ;
Huang, SA ;
Chien, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (12) :4741-4746
[5]   Vascular endothelial genes that are responsive to tumor necrosis factor-α in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes [J].
Horrevoets, AJG ;
Fontijn, RD ;
van Zonneveld, AJ ;
de Vries, CJM ;
ten Cate, JW ;
Pannekoek, H .
BLOOD, 1999, 93 (10) :3418-3431
[6]   Autophagy and human disease [J].
Huang, Ju ;
Klionsky, Daniel J. .
CELL CYCLE, 2007, 6 (15) :1837-1849
[7]   Senescence-associated genes in normal human oral keratinocytes [J].
Kang, MK ;
Kameta, A ;
Shin, KH ;
Baluda, MA ;
Kim, HR ;
Park, NH .
EXPERIMENTAL CELL RESEARCH, 2003, 287 (02) :272-281
[8]   Autophagy: Basic principles and relevance to disease [J].
Kundu, Mondira ;
Thompson, Craig B. .
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2008, 3 :427-455
[9]   Phosphoinositide recognition domains [J].
Lemmon, MA .
TRAFFIC, 2003, 4 (04) :201-213
[10]   Development by self-digestion: Molecular mechanisms and biological functions of autophagy [J].
Levine, B ;
Klionsky, DJ .
DEVELOPMENTAL CELL, 2004, 6 (04) :463-477