Chemiluminescence thrombin aptasensor using high-activity DNAzyme as catalytic label

被引:70
作者
Li, Tao [1 ,2 ]
Wang, Erkang [1 ,2 ]
Dong, Shaojun [1 ,2 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1039/b809296f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
With a designed high-activity DNAzyme as the catalytic label, an ultrasensitive chemiluminescence thrombin aptasensor is developed, enabling a 10- to 100-fold improvement in the detection sensitivity as compared with previous counterparts.
引用
收藏
页码:5520 / 5522
页数:3
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